an*, PING Qi-Neng РSchool of Pharmacy, China Pharmaceutical University, Nanjing 210009, China Р Р【ABSTRACT】 In the fields of drug delivery system, much attention has been focused on chitosan, which is patible, Рbiodegradable, and positive charge carrying, while the poor solubility in water limits its wide use. To improve its solubility Рand function, varities of chitosan derivatives have been synthesized. This article reviews the applications of modified chitosan Рin drug delivery system. Р【KEY WORDS】 Chitosan derivatives; Micelles; Gene carrier; Target; Oral; Smart material Р Р【Foundation Item】 This project wans supported be New Century Excellent Talents (No. NCET-06-0499) & Ministry of РEducation key project (No. 107062). Р Р464 Chin J Nat Med Nov. 2009 Vol. 7 No. 6 2009 年 11 月第 7 卷第 6 期
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