ed version to address this issue.2. The experiments are extensive in the present study. However, the author may wish to perform a further functional study to prove that the differential response in cells to SP-600125 is associated with their basal JNK2 expression. Answer: Yes, further functional study will be conducted to prove the correlation between basal JNK2 expression and cell response to SP-600125, eg. transfection of JNK2 siRNA or antisense. 3. There appear some illegal symbols, such as "20?, 37?, etc" in the Methods section. Answer: Corrections have been made in the revised version. 4. It is unclear why the author chose to use the dose of 20然 of SP-600125 for treatment of all cancer cell lines. It is mended that the authors shows a dose response curve for the different cell lines.
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