PKD )РParoxysmal movement disordersР发作性运动障碍(PD)(第2型)? 发作性肌张力异常的舞蹈手足徐动症? (paroxysmal dystonic choreoathetosis, PDC )或? 发作性非运动诱发的运动障碍? (paroxysmal non-kinesigenic dyskinesia,PNKD)РParoxysmal movement disordersР发作性运动障碍(PD)(第3型)?发作性持续运动诱发的肌张力障碍? (paroxysmal exercise-induced dystonia,PED) ? 发作性运动障碍(PD)(第4型)?夜间发作性肌张力障碍? (nocturnal paroxysmal dystonia,NPD)РParoxysmal movement disordersР发作性运动障碍病的分类Р 发作性共济失调(周期性共济失调)? 发作性共济失调1型(EA1)? 发作性共济失调2型(EA2) Р周期性共济失调3型(EA3)?周期性共济失调4型(EA4) ?周期性共济失调5型(EA5) ?周期性共济失调伴发作性舞蹈手足徐动和痉挛?周期性共济失调伴癫痫、偏头痛和交替性偏瘫РParoxysmal movement disordersР发作性震颤? (paroxysmal tremor, PT)РParoxysmal movement disordersР基因定位Р PKC: 16p11.2-q12.1 基因未明? 16q13-22.1? PDC: 2q31-36 myofibrillogenesis regulator 1 gene (MR-1) ? NPD: 20q13.2 CHRMA4? EA1: 12p13, KCNA1基因(钾离子通道)? EA2: 19p13, A1A 基因(钙离子通道)