re used in advance for removing the particles less than 37 μm, and the sand grinding and ic flotation separation are followed. The optimum particle fineness of 91.74% less than 75 μm is fixed, and the current of low intensity ic separation is 4 A. The roughing reagent system consists of sodium carbonate 2 kg/t, sodium hexametaphosphate 2 kg/t, sodium sulfide 13 kg/t and KPR 2 kg/t. By the closed circuit experiments, the zinc concentrate of zinc grade 27.89% and the recovery rate of 75.26%, and the iron concentrate of iron grade 61.25% and the recovery rate of 51.65% are obtained. And the functional mechanism of KPR with calamine is also analyzed based on the Zeta potential measurement. Key words: zinc oxide; washing; ic separation; flotation separation; zinc concentrate; iron concentrate