nganintroductorysection\rthatdefinesconceptsandterms,theclinical\rmanifestations,influences,andcostsofADEsare\rreviewed,alongwiththemedicationclasses,types,\randcausesofADEs.Informationsystemsthattarget\rdifferentstagesofthedrugorderinganddelivery\rprocessarediscussed.Differentstudiesshowthat\rcomputerizedphysicianorderentrysystemsare\ressentialinthepreventionofADEs.\rComputer-assisteddecisionsupportprogramsthatEvaluationWarning:ThedocumentwascreatedwithSpire.PDFfor.NET.\rareintegratedwithsystemsthatcovereachstageof\rthedrugorderinganddeliveryprocessprovidethe\rmostpowerfulpreventiontools.Throughcomparison\rwithothermethods,computer-basedinformation\rsystemsareshowntobethemostcost-effectiveand\rpromisingstrategyforpreventingADEs.Further\rchallengesandpossibleimprovementsarealso\rdiscussed.