rrierin order tostudy the mechanism ofskinphotodamage caused by solarultraviolet radiation.Meanwhile Trichophyton mentagrophytes infection model afterradiation was contructed in order to have afurtherunderstanding of theeffectand mechanism ofultraviolet radiation on fungal infections。 Chapter one"Determination ofminimal el-ythema doseoftheexperimental animals 1.Objective: To detectthemininlunlerythema dose ofC57BL/6,ICR mice andguinea pigs and determine which istheoptimal experimental a/limals. 2.Methods: We used SUV-1 000 sunlight simulator觞light source,and theMED determination Was divided into dosese indescending order ofeight irradiation hole. UVA andUVB outputpower Wasmeasured before eachirradiation.We had 0guinea pigs,each for agroup ofeight spotdose.Wehad 32 C57BL/6 and ICR mice were
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